KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP4K5
All Species:
24.24
Human Site:
T352
Identified Species:
48.48
UniProt:
Q9Y4K4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4K4
NP_006566.2
846
95040
T352
E
P
P
L
R
K
E
T
E
A
R
D
E
M
G
Chimpanzee
Pan troglodytes
XP_001155473
846
95023
T352
E
P
P
L
R
K
E
T
E
A
R
D
E
M
G
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
S21
L
K
K
L
D
E
D
S
L
T
K
Q
P
E
E
Dog
Lupus familis
XP_851371
846
95039
T352
E
P
P
L
R
K
E
T
E
A
R
D
E
M
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPM2
847
95026
T352
E
P
P
L
R
K
E
T
E
A
R
D
E
M
G
Rat
Rattus norvegicus
Q924I2
873
98660
T346
D
P
P
L
R
K
E
T
E
P
H
H
E
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515144
898
100018
T404
E
P
P
L
R
K
E
T
E
A
R
D
E
M
V
Chicken
Gallus gallus
Q5ZJK4
486
55318
S20
L
K
K
L
D
E
D
S
L
T
K
Q
P
E
E
Frog
Xenopus laevis
Q6IP06
493
56486
D27
K
Q
P
E
E
V
F
D
V
L
E
K
L
G
E
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
F26
T
K
Q
P
E
E
V
F
D
V
L
E
K
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
W202
T
V
I
G
T
P
F
W
M
A
P
E
V
I
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23356
1096
122486
V503
E
P
L
L
I
T
H
V
K
P
E
D
L
D
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
25.2
98.1
N.A.
95.9
68.7
N.A.
87
24.5
25.4
25
N.A.
25.8
N.A.
23.8
N.A.
Protein Similarity:
100
99.7
39.8
99
N.A.
98.2
81.3
N.A.
90
39.7
40.3
40.5
N.A.
43.2
N.A.
41
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
60
N.A.
93.3
6.6
6.6
6.6
N.A.
6.6
N.A.
26.6
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
100
73.3
N.A.
93.3
33.3
13.3
40
N.A.
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
17
0
17
9
9
0
0
50
0
9
9
% D
% Glu:
50
0
0
9
17
25
50
0
50
0
17
17
50
17
34
% E
% Phe:
0
0
0
0
0
0
17
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
42
% G
% His:
0
0
0
0
0
0
9
0
0
0
9
9
0
0
0
% H
% Ile:
0
0
9
0
9
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
9
25
17
0
0
50
0
0
9
0
17
9
9
0
0
% K
% Leu:
17
0
9
75
0
0
0
0
17
9
9
0
17
17
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
42
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
59
59
9
0
9
0
0
0
17
9
0
17
0
0
% P
% Gln:
0
9
9
0
0
0
0
0
0
0
0
17
0
0
0
% Q
% Arg:
0
0
0
0
50
0
0
0
0
0
42
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% S
% Thr:
17
0
0
0
9
9
0
50
0
17
0
0
0
0
0
% T
% Val:
0
9
0
0
0
9
9
9
9
9
0
0
9
0
17
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _